The William R Orthwein Jr And Laura
The organization is a private foundation dedicated to supporting a variety of causes, primarily focusing on arts and culture, education, health, and community services. It funds general operating expenses for nonprofits, including cultural institutions like the St. Louis Symphony Society and educational organizations such as MICDS. The foundation also supports health-related charities and initiatives aimed at human services, reflecting a commitment to enhancing community well-being. Its funding is predominantly directed towards organizations located in Missouri, indicating a strong regional focus.
Source: Zeffy Agent · Mar 2026
Ideal Applicant
Established Missouri-based nonprofit organizations seeking general operating support in arts, culture, education, health, or community services, typically mid-size or larger institutions able to receive six-figure or high-five-figure awards.
Good Fit
- • Organization is located in Missouri (especially the St. Louis area).
- • Request is for general operating support rather than a restricted project.
- • Organization has an established track record and capacity to absorb larger grants.
- • Ability to meet the application format: application form plus a two-page cover letter by June 1.
Geography
Giving is geographically concentrated: about 95% of dollars went to Missouri in the latest year, with only a handful of out-of-state grants across four other states.
Recipient Variety
The foundation funded a broad set of independent organizations (43 distinct recipients in 2024) across multiple sectors, with both repeat and new grantees despite top-five receipts capturing 40% of dollars.
New Applicants
Direct evidence of new entrants exists (13 new recipients in 2024) and the foundation publishes explicit application instructions, so unfamiliar applicants have a clear, realistic path to be considered.
Source: Zeffy Agent · Mar 2026
